A British study has found that having shingles can increase the risk for heart attacks.
The retrospective study, published in Neurology, included 106,601 shingles cases and 213,202 matched controls. The researchers followed the subjects for an average of 6.3 years after they contracted shingles.
After adjusting for body mass index, smoking, cholesterol, hypertension, diabetes and other vascular risk factors, they found that over all, having shingles increased the risk of a heart attack by 10 percent and the risk of a so-called mini-stroke, or transient ischemic attack, by 15 percent, though it did not alter the risk of having a major stroke.
But in people who developed shingles before age 40, the relative risks increased dramatically: a 2.4-fold increased risk for stroke, a 1.5-fold increase for transient ischemic attack, or T.I.A., and a 1.74-fold increase for heart attack.
The reasons are not completely clear, but the herpes zoster virus can spread to the blood vessels from the nerves and cause inflammation, which may lead to vascular disease.
"If you have shingles, get yourself checked for other vascular risks," said the lead author, Dr. Judith Breuer, a professor of virology at University College London. "We need to do more studies to figure out if preventing shingles is also a way of preventing stroke, heart attack and T.I.A.," she added. "But if you have other risk factors, you may want to consider the zoster vaccination."
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